In the mid-2000s, Indonesia became ‘ground zero’ for an outbreak of highly pathogenic avian influenza, the H5N1 strain, which global health experts feared would cause a devastating pandemic. When asked to participate in global health measures, Indonesia’s minister of health argued that the country had ‘viral sovereignty’ and refused to share samples with the World Health Organization’s Global Influenza Surveillance and Response System. The global health community claimed, in response, that such refusal put all humanity at risk. Both sides of the debate expressed paranoia, resentment, and mistrust as their different ideas of security came into play. In the midst of these accusations and counteraccusations, little attention was paid to the larger social and ecological context in which the virus had emerged and flourished. I argue that when vital matter gets taken up within frameworks of security, human and animal bodies, narratives, and politics get scripted through concerns for biological and political vulnerability. Paranoia, resentment, and mistrust resonate as the multiple vulnerabilities of bodies and their social positioning frame uncertain futures.